BDBM50252672 (S)-1-(4-Methanesulfonamidephenoxy)-3-(3,4-dichlorophenylethylamino)-2-propanol::CHEMBL492438

SMILES CS(=O)(=O)Nc1ccc(cc1)OC[C@H](CNCCc2ccc(c(c2)Cl)Cl)O

InChI Key InChIKey=GEFDXUZHLNJUMR-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50252672   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50252672((S)-1-(4-Methanesulfonamidephenoxy)-3-(3,4-dichlor...)
Affinity DataIC50: 50nMAssay Description:Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50252672((S)-1-(4-Methanesulfonamidephenoxy)-3-(3,4-dichlor...)
Affinity DataIC50: 730nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50252672((S)-1-(4-Methanesulfonamidephenoxy)-3-(3,4-dichlor...)
Affinity DataIC50: 500nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50252672((S)-1-(4-Methanesulfonamidephenoxy)-3-(3,4-dichlor...)
Affinity DataIC50: 500nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Emory University

Curated by ChEMBL
LigandPNGBDBM50252672((S)-1-(4-Methanesulfonamidephenoxy)-3-(3,4-dichlor...)
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed