BDBM50252394 CHEMBL4090165

SMILES ONC(=O)c1ccc(Cn2cc(nn2)-c2ccc(CN3CCCC3)cc2)cc1

InChI Key InChIKey=MTAWGBVDXCFYOF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50252394   

TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252394(CHEMBL4090165)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant human HDAC2 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252394(CHEMBL4090165)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human HDAC3 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252394(CHEMBL4090165)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252394(CHEMBL4090165)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252394(CHEMBL4090165)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-Lys (Ac)-AMC substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed