BDBM50252390 CHEMBL4104247

SMILES [H][C@]12CCCC[C@@]1([H])N(Cc1ccc(cc1)C(=O)NO)c1ccccc1S(=O)(=O)C2

InChI Key InChIKey=DMIDPYMXHVUIIM-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50252390   

TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC4 (627 to 1085 residues) expressed in baculovirus expression system using AMC-labeled RHKKAc as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC5 expressed in baculovirus expression system in Sf9 cells using AMC-labeled RHKKAc as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(acetyl)-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus expression system using AMC-labeled RHKKAc as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of full length human HDAC8 expressed in an E. coli expression system using AMC-labeled RHKAcKAc as substrate after 2 hrs by fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC10 (1 to 631 residues) expressed in baculovirus expression system in Sf9 cells RHKAcKAc after 2 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC11 expressed in baculovirus expression systemRHKAcKAc after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252390(CHEMBL4104247)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus expression system after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed