BDBM50252383 CHEMBL4105617

SMILES ONC(=O)c1cccc(c1)-c1csc(CSc2ccccc2)n1

InChI Key InChIKey=KWDXMPXINALNFB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50252383   

TargetHistone deacetylase 4(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252383(CHEMBL4105617)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252383(CHEMBL4105617)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252383(CHEMBL4105617)
Affinity DataIC50: 150nMAssay Description:Inhibition of HDAC8 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252383(CHEMBL4105617)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC1 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252383(CHEMBL4105617)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HDAC3 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252383(CHEMBL4105617)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC2 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252383(CHEMBL4105617)
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed