BDBM50252373 CHEMBL447723::Spheciosterol sulfate A

SMILES CCC(CC[C@@H](C)[C@H]1CC[C@@]2(C)[C@@H]3C[C@H](OS([O-])(=O)=O)[C@H]4[C@@H](O)[C@H](OS([O-])(=O)=O)[C@H](C[C@]4(C)C3=CC[C@]12C)OS([O-])(=O)=O)C(C)=C

InChI Key InChIKey=FMHAOQGZBOIUJA-UHFFFAOYSA-K

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252373   

TargetProtein kinase C zeta type(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252373(Spheciosterol sulfate A | CHEMBL447723)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of PKCzeta by TR-FRET based LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50252373(Spheciosterol sulfate A | CHEMBL447723)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of IL1-induced NF-kappaB P65 activation in human osteoarthritic primary chondrocytes preincubated 2 hrs before addition of IL1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed