BDBM50252304 (S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-methyl-6-(4-(4-(morpholine-4-carbonyl)piperazin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one::CHEMBL459118

SMILES Cc1cc(cc2[nH]c(nc12)-c1c(NC[C@@H](O)c2cccc(Cl)c2)cc[nH]c1=O)N1CCC(CC1)N1CCN(CC1)C(=O)N1CCOCC1

InChI Key InChIKey=XSBPOCYYAOOLIV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252304   

TargetInsulin-like growth factor 1 receptor(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50252304((S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(...)
Affinity DataIC50: 9nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Mouse)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50252304((S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(...)
Affinity DataIC50: 99nMAssay Description:Inhibition of IGF1R in mouse SAL cells assessed as thymidine incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50252304((S)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(...)
Affinity DataIC50: 19nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed