BDBM50252257 CHEMBL4092186

SMILES COc1ccc(NC(=S)NCCN2CCOCC2)cc1Cl

InChI Key InChIKey=GIWMAITYUJGWGK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50252257   

TargetAcetylcholinesterase(African malaria mosquito)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252257(CHEMBL4092186)
Affinity DataIC50: 190nMAssay Description:Inhibition of AChE1 in Anopheles gambiae head extract using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252257(CHEMBL4092186)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293F cells using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(African malaria mosquito)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252257(CHEMBL4092186)
Affinity DataIC50: 190nMAssay Description:Inhibition of AChE1 in Anopheles gambiae head extract using acetylthiocholine iodide as substrate measured over 60 secs by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(African malaria mosquito)
Ume£

Curated by ChEMBL
LigandPNGBDBM50252257(CHEMBL4092186)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant full length Anopheles gambiae AChE1 expressed in baculovirus-infected Sf9 insect cells using acetylthiocholine iodide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed