BDBM50252087 4-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl)methyl)benzonitrile::CHEMBL481513

SMILES COc1nccc(n1)-c1c(ncn1Cc1ccc(cc1)C#N)-c1ccc(F)cc1

InChI Key InChIKey=YXTDTSXIGHDYQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252087   

TargetMitogen-activated protein kinase 14(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50252087(4-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)...)
Affinity DataIC50: 859nMAssay Description:Inhibition of human recombinant p38alpha MAPK expressed in Escherichia coli by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50252087(4-((4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GST fused human recombinant ALK5 expressed in Sf9 cells by radioisotopic protein kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed