BDBM50251949 CHEMBL4094546

SMILES [#6]-[#6]1-[#6]\[#6](=[#6]/c2nc(-[#6])c(-[#6])nc2-[#6])\[#6](=[#7]/[#8])\[#6](\[#6]-1)=[#6]\c1nc(-[#6])c(-[#6])nc1-[#6]

InChI Key InChIKey=FSDZCBSBIUEMFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251949   

TargetEpidermal growth factor receptor(Human)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50251949(CHEMBL4094546)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50251949(CHEMBL4094546)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly preincubated with enzyme followed by GTP addition measured after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed