BDBM50251948 CHEMBL4075241

SMILES COc1cc(Cl)c(\C=C2/CN(C\C(=C/c3nc(C)c(C)nc3C)C2=O)C(C)C)cc1OC

InChI Key InChIKey=XJGBVDCXGFMFGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251948   

TargetEpidermal growth factor receptor(Human)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50251948(CHEMBL4075241)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50251948(CHEMBL4075241)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly preincubated with enzyme followed by GTP addition measured after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2019
Entry Details Article
PubMed