BDBM50251831 2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-pyran-4-yl)-N-(thiazol-2-yl)acrylamide::CHEMBL481166

SMILES CS(=O)(=O)c1ccc(cc1)C(=C/C1CCOCC1)\C(=O)Nc1nccs1

InChI Key InChIKey=HPFMVRXIWVGCSW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251831   

TargetHexokinase-4(Human)
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251831(2-(4-(methylsulfonyl)phenyl)-3-(tetrahydro-2H-pyra...)
Affinity DataEC50:  2.30E+3nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed