BDBM50251677 CHEMBL479577::N-(4-chlorophenyl)-4-(N'-cyano-N-{2-[(dimethylamino)methyl]phenyl}carbamimidoyl)-2-phenylpiperazine-1-carboxamide

SMILES CN(C)Cc1ccccc1N=C(NC#N)N1CCN(C(C1)c1ccccc1)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=UVEQLXUXABFFME-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251677   

TargetP2X purinoceptor 7(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251677(N-(4-chlorophenyl)-4-(N'-cyano-N-{2-[(dimethylamin...)
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251677(N-(4-chlorophenyl)-4-(N'-cyano-N-{2-[(dimethylamin...)
Affinity DataIC50: 1.07E+3nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed