BDBM50251640 4-[N-(1-benzofuran-4-yl)-N'-cyanocarbamimidoyl]-N-(3-fluorophenyl)-3-(propan-2-yl)piperazine-1-carboxamide::CHEMBL517225

SMILES CC(C)C1CN(CCN1C(NC#N)=Nc1cccc2occc12)C(=O)Nc1cccc(F)c1

InChI Key InChIKey=SFZVHHKYWQIXCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251640   

TargetP2X purinoceptor 7(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251640(4-[N-(1-benzofuran-4-yl)-N'-cyanocarbamimidoyl]-N-...)
Affinity DataIC50: 2.49E+4nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed