BDBM50251623 4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)amino)pyrrolidin-1-yl)methyl)benzoic acid::CHEMBL481489

SMILES CN(CC(=O)Nc1ccc(Oc2ccccc2)cc1)C1CCN(Cc2ccc(cc2)C(O)=O)C1

InChI Key InChIKey=HOCMQHWZEDLVLB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50251623   

TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251623(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)
Affinity DataIC50: 57nMAssay Description:Inhibition of LTA4 hydrolase by hydrolase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251623(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)
Affinity DataIC50: 57nMAssay Description:Inhibition of LTA4 hydrolase by hydrolase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251623(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)
Affinity DataIC50: 220nMAssay Description:Inhibition of LTA4 hydrolase by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50251623(4-((3-(methyl(2-oxo-2-(4-phenoxyphenylamino)ethyl)...)
Affinity DataIC50: 220nMAssay Description:Inhibition of LTA4 hydrolase by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed