BDBM50251590 CHEMBL4078380

SMILES ONC(=O)\C=C\c1ccc(CCNC(=O)c2ccc3OCOc3c2)cc1

InChI Key InChIKey=JRPTYRWYKMRIIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251590   

TargetHistone deacetylase 1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50251590(CHEMBL4078380)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 15 mins followed by substrate addition measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50251590(CHEMBL4078380)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of HDAC6 (unknown origin) preincubated for 15 mins followed by substrate addition measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed