BDBM50251565 1-((4-((4-chlorophenyl)carbamoyl)-3-phenylpiperazin-1-yl)(o-toluidino)methylene)urea::CHEMBL511126

SMILES Cc1ccccc1N=C(NC(N)=O)N1CCN(C(C1)c1ccccc1)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=RZWJRHSLQGOBCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251565   

TargetP2X purinoceptor 7(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251565(1-((4-((4-chlorophenyl)carbamoyl)-3-phenylpiperazi...)
Affinity DataIC50: 6.40E+3nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251565(1-((4-((4-chlorophenyl)carbamoyl)-3-phenylpiperazi...)
Affinity DataIC50: 1.03E+4nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed