BDBM50251563 4-(4-chlorobenzyl)-N'-cyano-3-phenyl-N-o-tolylpiperazine-1-carboxamidine::CHEMBL472135

SMILES Cc1ccccc1N=C(NC#N)N1CCN(Cc2ccc(Cl)cc2)C(C1)c1ccccc1

InChI Key InChIKey=UOCNLBMTDJNNOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251563   

TargetP2X purinoceptor 7(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251563(4-(4-chlorobenzyl)-N'-cyano-3-phenyl-N-o-tolylpipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251563(4-(4-chlorobenzyl)-N'-cyano-3-phenyl-N-o-tolylpipe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed