BDBM50251533 CHEMBL518308::N-(4-chlorophenyl)-4-(N'-cyano-N-o-tolylcarbamimidoyl)-2-phenylpiperazine-1-carboxamide::N-(4-chlorophenyl)-4-[N'-cyano-N-(2-methylphenyl)carbamimidoyl]-2-phenylpiperazine-1-carboxamide

SMILES Cc1ccccc1N=C(NC#N)N1CCN(C(C1)c1ccccc1)C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=SCWHRLVRDTZVDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251533   

TargetP2X purinoceptor 7(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251533(N-(4-chlorophenyl)-4-[N'-cyano-N-(2-methylphenyl)c...)
Affinity DataIC50: 132nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50251533(N-(4-chlorophenyl)-4-[N'-cyano-N-(2-methylphenyl)c...)
Affinity DataIC50: 95nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed