BDBM50251421 (R)-2-(4-(cyclobutylsulfonyl)phenyl)-N-(5-fluorothiazol-2-yl)-3-(tetrahydro-2H-pyran-4-yl)propanamide::CHEMBL519273

SMILES Fc1cnc(NC(=O)[C@H](CC2CCOCC2)c2ccc(cc2)S(=O)(=O)C2CCC2)s1

InChI Key InChIKey=DWIPGNHOTXSYBW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50251421   

TargetHexokinase-4(Human)
(Osi) Prosidion

Curated by ChEMBL
LigandPNGBDBM50251421((R)-2-(4-(cyclobutylsulfonyl)phenyl)-N-(5-fluoroth...)
Affinity DataEC50:  140nMAssay Description:Activation of GST fused human liver glucokinase assessed as generation of NADPH by G6PDH coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed