BDBM50251393 CHEMBL519266::Rhynchophylline

SMILES CC[C@H]1CN2CC[C@@]3([C@@H]2C[C@@H]1\C(=C/OC)C(=O)OC)C(=O)Nc1ccccc31

InChI Key InChIKey=DAXYUDFNWXHGBE-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50251393   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Medical University

Curated by ChEMBL
LigandPNGBDBM50251393(Rhynchophylline | CHEMBL519266)
Affinity DataIC50: 7.73E+5nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50251393(Rhynchophylline | CHEMBL519266)
Affinity DataEC50:  1.03E+4nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHOK1 cells incubated for 16 hrs followed by forskolin-stimulation and measured after 2 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50251393(Rhynchophylline | CHEMBL519266)
Affinity DataEC50:  1.03E+4nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHOK1 cells incubated for 16 hrs followed by forskolin-stimulation and measured after 2 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50251393(Rhynchophylline | CHEMBL519266)
Affinity DataEC50:  17nMAssay Description:Agonist activity at 5HT1A (unknown origin) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed