BDBM50251198 CHEMBL4079783

SMILES Cc1cc(n[nH]1)Nc2c3cc(ccc3nc(n2)C(=O)N4CCN[C@@H](C4)C)Cl

InChI Key InChIKey=WQTMYTFWTYPJST-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251198   

TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251198(CHEMBL4079783)
Affinity DataKi:  51nMAssay Description:Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PAK 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251198(CHEMBL4079783)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human PAK1 kinase domain using coumarin and fluorescein-labeled ser/thr19 peptide as substrate preincubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed