BDBM50251177 CHEMBL4090268

SMILES CC1CN(CC(C)N1)C(=O)c1nc(Nc2cc([nH]n2)C2CC2)c2cc(Cl)ccc2n1

InChI Key InChIKey=VIRGBRQFVJELSV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251177   

TargetSerine/threonine-protein kinase PAK 4(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251177(CHEMBL4090268)
Affinity DataKi:  114nMAssay Description:Inhibition of human PAK4 kinase domain using coumarin and fluorescein-labeled ser/thr20 peptide as substrate preincubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251177(CHEMBL4090268)
Affinity DataKi: >4.52E+3nMAssay Description:Inhibition of human PAK1 kinase domain using coumarin and fluorescein-labeled ser/thr19 peptide as substrate preincubated for 15 mins followed by ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed