BDBM50251095 CHEMBL4077930

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)c4ccccc34)c2cc1OC

InChI Key InChIKey=CKEJPGSKHUMMNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251095   

TargetVascular endothelial growth factor receptor 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50251095(CHEMBL4077930)
Affinity DataIC50: 29nMAssay Description:Inhibition of VEGFR2 (unknown origin) using biotin substrate incubated for 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50251095(CHEMBL4077930)
Affinity DataIC50: 86nMAssay Description:Inhibition of EGFR (unknown origin) using biotin as substrate incubated for 1 hrs in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50251095(CHEMBL4077930)
Affinity DataIC50: 84nMAssay Description:Inhibition of FGFR4 (unknown origin) using biotin as substrate incubated for 1 hrs in the presence of ATP by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed