BDBM50251028 (R)-(-)-2-Methyl-apomorphine hydrochloride::CHEMBL507567::CHEMBL557547

SMILES CN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31

InChI Key InChIKey=QRJZCXSRTBCYIW-UHFFFAOYSA-N

Data  4 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50251028   

TargetD(2) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251028(CHEMBL507567 | CHEMBL557547 | (R)-(-)-2-Methyl-apo...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2 receptor in brain striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251028(CHEMBL507567 | CHEMBL557547 | (R)-(-)-2-Methyl-apo...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251028(CHEMBL507567 | CHEMBL557547 | (R)-(-)-2-Methyl-apo...)
Affinity DataKi:  20.7nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2short receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251028(CHEMBL507567 | CHEMBL557547 | (R)-(-)-2-Methyl-apo...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2 receptor in brain striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251028(CHEMBL507567 | CHEMBL557547 | (R)-(-)-2-Methyl-apo...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251028(CHEMBL507567 | CHEMBL557547 | (R)-(-)-2-Methyl-apo...)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed