BDBM50251026 (R)-(-)-2-Phenyl-apomorphine hydrochloride::CHEMBL458397::CHEMBL465054

SMILES CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1

InChI Key InChIKey=NJWHLJABYCIZPL-UHFFFAOYSA-N

Data  5 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50251026   

TargetD(3) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251026(CHEMBL465054 | CHEMBL458397 | (R)-(-)-2-Phenyl-apo...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251026(CHEMBL465054 | CHEMBL458397 | (R)-(-)-2-Phenyl-apo...)
Affinity DataIC50: 23nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2 receptor in brain striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251026(CHEMBL465054 | CHEMBL458397 | (R)-(-)-2-Phenyl-apo...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at rat dopamine D2short receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251026(CHEMBL465054 | CHEMBL458397 | (R)-(-)-2-Phenyl-apo...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in SF9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251026(CHEMBL465054 | CHEMBL458397 | (R)-(-)-2-Phenyl-apo...)
Affinity DataKi:  11.7nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2short receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251026(CHEMBL465054 | CHEMBL458397 | (R)-(-)-2-Phenyl-apo...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]spiperone from rat dopamine D2 receptor in brain striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Debrecen

Curated by ChEMBL
LigandPNGBDBM50251026(CHEMBL465054 | CHEMBL458397 | (R)-(-)-2-Phenyl-apo...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]raclopride from human cloned dopamine D2 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
University of Tartu

Curated by ChEMBL
LigandPNGBDBM50251026(CHEMBL465054 | CHEMBL458397 | (R)-(-)-2-Phenyl-apo...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in Ltk deficient fibroblast cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed