BDBM50251024 CHEMBL457486::N-(3,5-Difluoro-4-hydroxyphenyl)-4-nitrobenzenesulfonamide

SMILES Oc1c(F)cc(NS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)cc1F

InChI Key InChIKey=WAUVOCPAFUJJNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251024   

TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251024(N-(3,5-Difluoro-4-hydroxyphenyl)-4-nitrobenzenesul...)
Affinity DataIC50: 4.44E+4nMAssay Description:Inhibition of aldose reductase in rat lensesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251024(N-(3,5-Difluoro-4-hydroxyphenyl)-4-nitrobenzenesul...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251024(N-(3,5-Difluoro-4-hydroxyphenyl)-4-nitrobenzenesul...)
Affinity DataIC50: 4.44E+4nMAssay Description:Inhibition of Fischer-344 rat lens ALR2 by least-square analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed