BDBM50251023 CHEMBL458568::N-(3,5-Difluoro-4-hydroxyphenyl)benzenesulfonamide

SMILES Oc1c(F)cc(NS(=O)(=O)c2ccccc2)cc1F

InChI Key InChIKey=YAWFBTGILXVPSB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251023   

TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251023(N-(3,5-Difluoro-4-hydroxyphenyl)benzenesulfonamide...)
Affinity DataIC50: 3.29E+4nMAssay Description:Inhibition of aldose reductase in rat lensesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251023(N-(3,5-Difluoro-4-hydroxyphenyl)benzenesulfonamide...)
Affinity DataIC50: 3.29E+4nMAssay Description:Inhibition of Fischer-344 rat lens ALR2 by least-square analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Rat)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50251023(N-(3,5-Difluoro-4-hydroxyphenyl)benzenesulfonamide...)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed