BDBM50251013 2,4,2',4'-tetrahydroxy-3'-prenylchalcone::CHEMBL465880::morachalcone A

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])ccc(-[#6](=O)\[#6]=[#6]\c2ccc(-[#8])cc2-[#8])c1-[#8]

InChI Key InChIKey=XJBDQRZHVWHALU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50251013   

TargetAromatase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50251013(morachalcone A | 2,4,2',4'-tetrahydroxy-3'-prenylc...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of aromatase from human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPancreatic triacylglycerol lipase(Pig)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50251013(morachalcone A | 2,4,2',4'-tetrahydroxy-3'-prenylc...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of porcine pancreatic lipase using p-nitrophenylbutyrate as substrate assessed as formation of p-nitrophenol preincubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2016
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50251013(morachalcone A | 2,4,2',4'-tetrahydroxy-3'-prenylc...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50251013(morachalcone A | 2,4,2',4'-tetrahydroxy-3'-prenylc...)
Affinity DataIC50: 80nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50251013(morachalcone A | 2,4,2',4'-tetrahydroxy-3'-prenylc...)
Affinity DataIC50: 80nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetTyrosinase(Mouse)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50251013(morachalcone A | 2,4,2',4'-tetrahydroxy-3'-prenylc...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed