BDBM50250874 CHEMBL4089107

SMILES OC(=O)c1ccc2nc(sc2c1)N1CC[C@H](C1)OCc1c(onc1-c1c(Cl)cccc1Cl)C1CC1

InChI Key InChIKey=KLUBVOZTWKPXPP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250874   

TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50250874(CHEMBL4089107)
Affinity DataEC50:  9.20E+3nMAssay Description:Agonist activity at recombinant human GST-tagged FXR ligand binding domain (193 to 472 residues) expressed in baculovirus infected insect cells asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50250874(CHEMBL4089107)
Affinity DataEC50:  3.06E+3nMAssay Description:Agonist activity at recombinant human GST-tagged FXR ligand binding domain (193 to 472 residues) expressed in baculovirus infected insect cells asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed