BDBM50250620 CHEMBL4084786

SMILES CC(C)Cc1ccc(COc2ccc3C(C)=C(CN4CC(C4)C(O)=O)CCc3c2)c(F)c1

InChI Key InChIKey=SOUWOUHKLYNOQG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250620   

TargetSphingosine 1-phosphate receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50250620(CHEMBL4084786)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO-K1 cells assessed as increase in S1P-stimulated calcium influx preincubated for 5 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50250620(CHEMBL4084786)
Affinity DataEC50: >3.00E+4nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed