BDBM50250277 CHEMBL4104932

SMILES Clc1cc(Cl)c(C(=O)NC2CCN(Cc3ccccc3)CC2)c(Cl)c1

InChI Key InChIKey=RRDWZHLGSMFGLN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50250277   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250277(CHEMBL4104932)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse GAT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250277(CHEMBL4104932)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250277(CHEMBL4104932)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250277(CHEMBL4104932)
Affinity DataIC50: 1.70E+6nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250277(CHEMBL4104932)
Affinity DataIC50: 1.70E+6nMAssay Description:Inhibition of mouse GAT2 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250277(CHEMBL4104932)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of mouse GAT3 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250277(CHEMBL4104932)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mouse BGT1 expressed in HEK293 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed