BDBM50250253 CHEMBL4080696

SMILES Fc1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=XQQCWHHHQWVAGC-UHFFFAOYSA-N

Data  3 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50250253   

TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human GAT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human GAT2 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human GAT3 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetSodium- and chloride-dependent betaine transporter(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BGT1 expresses in tsA201 cells assessed as reduction in [3H]GABA uptake after 3 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2019
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataIC50: 4.30E+4nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-pentazocine from Sigma 1-receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-(+)-pentazocine from Dunkin-Hartley guinea pig brain cortex Sigma 1 receptor incubated for 150 mins by liquid scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50250253(CHEMBL4080696)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from Sigma 2-receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed