BDBM50250246 CHEMBL4059591

SMILES COC(=O)c1ccc(OCCN2CCOCC2)c(NC(=O)COc2ccc(cc2)C(C)(C)CC(C)(C)C)c1

InChI Key InChIKey=FJFDLLGXWZXSGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250246   

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50250246(CHEMBL4059591)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Human)
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50250246(CHEMBL4059591)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details Article
PubMed