BDBM50249797 CHEMBL4059509

SMILES CCc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(CC)c1=O

InChI Key InChIKey=QTIVTZLLONAWRR-UHFFFAOYSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50249797   

TargetATPase family AAA domain-containing protein 2(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ATAD2A expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetPeregrin(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BRPF1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 9(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BRD9 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human His tagged CECR2 incubated for 30 mins followed by addition of biotinylated peptide and further incubation for 30 mins measured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetNucleosome-remodeling factor subunit BPTF(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human His tagged FALZ incubated for 30 mins followed by addition of biotinylated peptide and further incubation for 30 mins measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human His tagged TAF1A incubated for 30 mins followed by addition of biotinylated peptide and further incubation for 30 mins measured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 7(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BRD7 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 1(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BRPF2-BRD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain and PHD finger-containing protein 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BRPF3 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BRD4-BD1 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetProbable global transcription activator SNF2L2(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of human SMARCA2A expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2B(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ATAD2B expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetPeregrin(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human His tagged BRPF1 incubated for 30 mins followed by addition of biotinylated peptide and further incubation for 30 mins measured b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 9(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human His tagged BRD9 incubated for 30 mins followed by addition of biotinylated peptide and further incubation for 30 mins measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human His tagged BRD4-BD1 incubated for 30 mins followed by addition of biotinylated peptide and further incubation for 30 mins measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CREBBP expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PCAF expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetBromodomain adjacent to zinc finger domain protein 2A(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BAZ2A expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase TRIM33(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human TRIM33 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed
TargetChromatin remodeling regulator CECR2(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50249797(CHEMBL4059509)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CECR2 expressed in Escherichia coli BL21 after 1 hr by BROMOscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2020
Entry Details Article
PubMed