BDBM50249653 CHEMBL4079597

SMILES Cc1cnc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)o1

InChI Key InChIKey=SOQXYEGWTMCTSF-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249653   

TargetToll-like receptor 7(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50249653(CHEMBL4079597)
Affinity DataEC50:  100nMAssay Description:Agonist activity at TLR7 in human PBMC assessed as induction of IFNalpha-mediated inhibition of HCV genotype 1b RNA replication in human HuH luc/neo ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50249653(CHEMBL4079597)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of 3H-dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed