BDBM50249582 CHEMBL1547178::US10729695, Compound CB-13

SMILES Cc1c(Cl)cccc1NC(=O)CNC(=O)c1ccccc1F

InChI Key InChIKey=NXYXFWPAWIMCPX-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249582   

TargetAdvanced glycosylation end product-specific receptor(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249582(CHEMBL1547178 | US10729695, Compound CB-13)
Affinity DataKd:  32nMAssay Description:Inhibition of CML binding to RAGE (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2019
Entry Details Article
PubMed
TargetAdvanced glycosylation end product-specific receptor(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM50249582(CHEMBL1547178 | US10729695, Compound CB-13)
Affinity DataKd:  123nMAssay Description:Day 1Step 1. Add 50 μl anti-mDial (1:160 dilution in 0.1M NaHCO3 pH 9.6)/well. Incubate overnight at 4° C.Day 2Step 2. Use the plate washer to a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent