BDBM50249485 2-((1-(biphenyl-4-ylsulfonyl)piperidin-4-yl)methyl)-1H-benzo[d]imidazole::CHEMBL473235

SMILES O=S(=O)(N1CCC(Cc2nc3ccccc3[nH]2)CC1)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=IBBDXGXVTHJLDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249485   

Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249485(2-((1-(biphenyl-4-ylsulfonyl)piperidin-4-yl)methyl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249485(2-((1-(biphenyl-4-ylsulfonyl)piperidin-4-yl)methyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed