BDBM50249460 CHEMBL472416::biphenyl-4-yl(4-(1-methyl-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)methanone

SMILES Cn1c(nc2ccccc12)C1CCN(CC1)C(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=VFQQFISLAQAPEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249460   

Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249460(biphenyl-4-yl(4-(1-methyl-1H-benzo[d]imidazol-2-yl...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249460(biphenyl-4-yl(4-(1-methyl-1H-benzo[d]imidazol-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed