BDBM50249210 4-(5-methyl-1H-pyrazol-3-ylamino)-2-(2,2,2-trifluoroethyl)phthalazin-1(2H)-one::CHEMBL470718

SMILES Cc1cc(Nc2nn(CC(F)(F)F)c(=O)c3ccccc23)[nH]n1

InChI Key InChIKey=ZKNCQUCCUXIJKY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249210   

TargetAurora kinase B(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50249210(4-(5-methyl-1H-pyrazol-3-ylamino)-2-(2,2,2-trifluo...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Aurora B by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50249210(4-(5-methyl-1H-pyrazol-3-ylamino)-2-(2,2,2-trifluo...)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of recombinant SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Evotec (Uk)

Curated by ChEMBL
LigandPNGBDBM50249210(4-(5-methyl-1H-pyrazol-3-ylamino)-2-(2,2,2-trifluo...)
Affinity DataIC50: 66nMAssay Description:Inhibition of Aurora A by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed