BDBM50249186 CHEMBL472802::N-(2,6-dimethylphenyl)-4-(4-phenylpyrido[2,3-d]pyrimidin-2-ylamino)benzamide

SMILES Cc1cccc(C)c1NC(=O)c1ccc(Nc2nc(-c3ccccc3)c3cccnc3n2)cc1

InChI Key InChIKey=TXSXINTUVJDFKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249186   

TargetSonic hedgehog protein(Mouse)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50249186(N-(2,6-dimethylphenyl)-4-(4-phenylpyrido[2,3-d]pyr...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of SHH-mediated mouse C3H10T1/2 cells differentiation into osteoblasts by alkaline phosphatase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed