BDBM50249175 3-(4-(1H-benzo[d]imidazol-2-yl)piperidine-1-carbonyl)-6-phenylpyridin-2(1H)-one::CHEMBL473187

SMILES O=C(N1CCC(CC1)c1nc2ccccc2[nH]1)c1ccc([nH]c1=O)-c1ccccc1

InChI Key InChIKey=IVLWBLYHPAQTOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249175   

Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249175(3-(4-(1H-benzo[d]imidazol-2-yl)piperidine-1-carbon...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249175(3-(4-(1H-benzo[d]imidazol-2-yl)piperidine-1-carbon...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux by aequorin lumin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed