BDBM50249102 4,4',4'',4'''-(thiophene-2,3,4,5-tetrayl)tetrapyridine::4-(3,4,5-tri(pyridin-4-yl)thiophen-2-yl)pyridine::CHEMBL472994

SMILES c1cc(ccn1)-c1sc(c(c1-c1ccncc1)-c1ccncc1)-c1ccncc1

InChI Key InChIKey=USWLOKMMUTWFMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249102   

TargetSonic hedgehog protein(Mouse)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50249102(4-(3,4,5-tri(pyridin-4-yl)thiophen-2-yl)pyridine |...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells by GLI-responsive firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetZinc finger protein GLI2(Mouse)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50249102(4-(3,4,5-tri(pyridin-4-yl)thiophen-2-yl)pyridine |...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GLI1/GLI2 in mouse Shh Light2 cells assessed as reduction in endogenous hedgehog signalling in presence of Smo agonist SAG by luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed