BDBM50248887 2-(2,4-Difluoro-phenylamino)-dibenzo[a,d]cyclohepten-5-one::CHEMBL515727

SMILES Fc1ccc(Nc2ccc3c(c2)ccc2ccccc2c3=O)c(F)c1

InChI Key InChIKey=HQDWZDZNCCZBRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248887   

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50248887(2-(2,4-Difluoro-phenylamino)-dibenzo[a,d]cyclohept...)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibition of p38alpha MAPK by cell-free enzyme immunosorbent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-UniversitäT

Curated by ChEMBL
LigandPNGBDBM50248887(2-(2,4-Difluoro-phenylamino)-dibenzo[a,d]cyclohept...)
Affinity DataIC50: 4.20E+3nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed