BDBM50248844 CHEMBL474192::N-(4-tert-Butylbenzyl)-N'-[6-methoxy-5-(methylsulfonylamino)-1-indanyl]thiourea

SMILES COc1cc2C(CCc2cc1NS(C)(=O)=O)NC(=S)NCc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=ROVRBXREIUKAQI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248844   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50248844(N-(4-tert-Butylbenzyl)-N'-[6-methoxy-5-(methylsulf...)
Affinity DataKi:  3.37E+3nMAssay Description:Displacement of [3H]resiniferatoxin from rat TRPV1 expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50248844(N-(4-tert-Butylbenzyl)-N'-[6-methoxy-5-(methylsulf...)
Affinity DataKi:  2.50E+4nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as capsaicin-stimulated 45Ca2+ uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed