BDBM50248843 CHEMBL474191::N-(4-tert-Butylbenzyl)-N'-[5-methoxy-6-(methylsulfonylamino)-1,2,3,4-tetrahydro-1-naphthyl]thiourea

SMILES COc1c(NS(C)(=O)=O)ccc2C(CCCc12)NC(=S)NCc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=SZNFIHWYZNOFGZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248843   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50248843(N-(4-tert-Butylbenzyl)-N'-[5-methoxy-6-(methylsulf...)
Affinity DataKi:  1.75E+3nMAssay Description:Displacement of [3H]resiniferatoxin from rat TRPV1 expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50248843(N-(4-tert-Butylbenzyl)-N'-[5-methoxy-6-(methylsulf...)
Affinity DataKi:  4.70E+3nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as capsaicin-stimulated 45Ca2+ uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed