BDBM50248813 CHEMBL474773::N-(4-tert-Butylbenzyl)-N'-[4-methoxy-5-(methylsulfonylamino)-1-indanyl] thiourea

SMILES COc1c2CCC(NC(=S)NCc3ccc(cc3)C(C)(C)C)c2ccc1NS(C)(=O)=O

InChI Key InChIKey=OHUQTXKKRXPGRG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248813   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50248813(N-(4-tert-Butylbenzyl)-N'-[4-methoxy-5-(methylsulf...)
Affinity DataKi:  1.69E+3nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed as capsaicin-stimulated 45Ca2+ uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50248813(N-(4-tert-Butylbenzyl)-N'-[4-methoxy-5-(methylsulf...)
Affinity DataKi:  1.82E+3nMAssay Description:Displacement of [3H]resiniferatoxin from rat TRPV1 expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed