BDBM50248606 3',5'-dichloro-4-(2-phenylpropan-2-yl)biphenyl-2,6-diol::CHEMBL525067::US9139546, 41

SMILES CC(C)(c1ccccc1)c1cc(O)c(c(O)c1)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=WRPLLIGFYQLTCL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248606   

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248606(3',5'-dichloro-4-(2-phenylpropan-2-yl)biphenyl-2,6...)
Affinity DataKi:  1.07nM ΔG°:  -12.4kcal/moleT: 2°CAssay Description:15.3 ug of membranes (20 ul of 1:20 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248606(3',5'-dichloro-4-(2-phenylpropan-2-yl)biphenyl-2,6...)
Affinity DataKi:  1.07nMAssay Description:Binding affinity to human CB2 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248606(3',5'-dichloro-4-(2-phenylpropan-2-yl)biphenyl-2,6...)
Affinity DataKi:  93.7nM ΔG°:  -9.74kcal/moleT: 2°CAssay Description:8 ug of membranes (20 ul of 1:8 dilution in incubation buffer) was incubated with 5 ul of drug solution (10E-4M to 10E-12M) and 5ul of 5.4 nM [3H]CP5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
The University of Tennessee Research Foundation

US Patent
LigandPNGBDBM50248606(3',5'-dichloro-4-(2-phenylpropan-2-yl)biphenyl-2,6...)
Affinity DataKi:  93.7nMAssay Description:Binding affinity to human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed