BDBM50248583 3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-3-yl)-N-(3,4-difluorophenylsulfonyl)acrylamide::CHEMBL461390

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(F)c(Cl)c3)cccc12

InChI Key InChIKey=OXHRJHPEGGXCMA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50248583   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248583(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radioligand from EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248583(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radioligand from EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248583(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of radioligand from IP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin F2-alpha receptor(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248583(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 1.82E+3nMAssay Description:Displacement of radioligand from FP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248583(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 26.9nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248583(3-(4-(3-chloro-4-fluorophenoxy)-1-methyl-1H-indol-...)
Affinity DataIC50: 81.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed