BDBM50248568 4-(1-(((3R)-3-methyl-4-(4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenylsulfonyl)piperazin-1-yl)methyl)cyclopropyl)benzamide::CHEMBL516636

SMILES C[C@@H]1CN(CC2(CC2)c2ccc(cc2)C(N)=O)CCN1S(=O)(=O)c1ccc(cc1)C(C)(O)C(F)(F)F

InChI Key InChIKey=PJIHPWDQNLPHQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50248568   

LigandPNGBDBM50248568(4-(1-(((3R)-3-methyl-4-(4-(1,1,1-trifluoro-2-hydro...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50248568(4-(1-(((3R)-3-methyl-4-(4-(1,1,1-trifluoro-2-hydro...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed