BDBM50248555 3-((2-(9H-xanthen-9-yl)ethyl)(methyl)amino)-1-(4-(3,4-difluorophenyl)piperazin-1-yl)propan-1-one::CHEMBL460542

SMILES CN(CCC1c2ccccc2Oc2ccccc12)CCC(=O)N1CCN(CC1)c1ccc(F)c(F)c1

InChI Key InChIKey=FBLFUQVNJABTNK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248555   

TargetCytochrome P450 1A2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50248555(3-((2-(9H-xanthen-9-yl)ethyl)(methyl)amino)-1-(4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP1A2 by microplate-based direct fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50248555(3-((2-(9H-xanthen-9-yl)ethyl)(methyl)amino)-1-(4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 by microplate-based direct fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50248555(3-((2-(9H-xanthen-9-yl)ethyl)(methyl)amino)-1-(4-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19 by microplate-based direct fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed